Evidence that estrogen-receptor-negative, progesterone-receptor-positive breast and ovarian carcinomas contain estrogen receptor
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چکیده
منابع مشابه
ADENOSINE DEAMINASE ACTIVITY IN ESTROGEN RECEPTOR POSITIVE AND NEGATIVE HUMAN BREAST CANCER CELL LINES
ABSTRACT Background: The aims of this study were to assay the activity of adenosine deaminase (ADA) in estrogen receptor positive (MCF-7) and negative (MDA-MB468) breast cancer cell lines. Methods: MDA-MB468 and MCF-7 breast cancer cell lines were cultured in complete medium, striped serum with and without 0.0 1~-LM diethylstilbestrol (DES), complete medium in the presence and absence of 111M ...
متن کاملOutcomes of Estrogen Receptor Negative and Progesterone Receptor Positive Breast Cancer
PURPOSE To describe the clinical features and outcomes of estrogen receptor negative (ER-) and progesterone receptor positive (PgR+) breast cancer. METHODS We retrospectively reviewed a well-characterized database of sequential patients diagnosed with early stage invasive breast carcinoma. Outcomes of interest were time to relapse (TTR) and overall survival (OS). Multivariable Cox proportiona...
متن کاملProgesterone receptor status in determining the prognosis of estrogen receptor positive/ HER2 negative breast carcinoma patients.
PURPOSE To evaluate the impact of progesterone receptor (PR) status on estrogen receptor (ER)-positive and HER2-negative breast cancer. METHODS A total of 1673 operable breast cancer patients, diagnosed from June 1984 to June 2011 were retrospectively reviewed and 400 patients with ER-positive and HER2-negative tumors were identified and evaluated. ER-positive and HER2-negative patients were ...
متن کاملQuantification of Argyrophilic Nucleolar Organizer Regions in Estrogen Receptor Positive and Estrogen Receptor Negative Ductal Breast Carcinomas
Argyrophilic nucleolar organizer regions (AgNORs) analysis of 20 estrogen receptor positive (ER+) and 16 estrogen receptor negative (ER-) invasive ductal breast carcinomas was performed. The quantification of AgNORs was determined by using morphometrical method in three ways: 1) mean number of AgNORs per nucleus counted on a 100 random nuclei, 2) mean number of AgNORs per nucleus counted on 200...
متن کاملRB in breast cancer: differential effects in estrogen receptor-positive and estrogen receptor-negative disease.
The RB pathway is one of the best-studied and most frequently altered pathways leading to loss of proliferative control in cancer. it can be disrupted by a variety of means including, but not limited to, epigenetic silencing, allelic loss or mutation of RB1. in some cancers including breast cancer, amplification of the CCND1 gene or overexpression of cyclin D1 is commonly observed.1 in others, ...
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ژورنال
عنوان ژورنال: Cancer
سال: 1981
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19810901)48:5<1215::aid-cncr2820480527>3.0.co;2-3